Announcement of paper by Albert Basson:
Dr. Albert Basson from King’s College London, and his research group, recently published a seminal study in the Journal of Clinical Investigation entitled “The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression”. In the study, they show that CHD7, the gene disrupted in CHARGE syndrome, contributes to development of the cerebellum, a critical brain structure that controls movement, cognition, and processing of sensory information. They show that loss of CHD7 regulates other genes known to be involved in cerebellar function, and that mice with reduced levels of CHD7 have abnormalities in cerebellar development. Dr. Basson is a recipient of a 2016 CHARGE research pilot award from the foundation. We congratulate him and his colleagues on their achievements.
